Show HN: AIDO.ModelGenerator and Expanded Foundation Model Suite
genbio.aiGenBio AI just released an update to AIDO.ModelGenerator, a software package for adapting, benchmarking, and applying biological foundation models across multiple tasks and data types.
What it is
AIDO.ModelGenerator supports both GenBio AI models and popular open-source models like Enformer, ESM2, and scFoundation. It enables workflows for structure prediction, protein modeling, single-cell analysis, and spatial transcriptomics.
What’s new
New models:
• AIDO.StructurePrediction – biomolecular structure prediction across proteins, RNA, DNA, and ligands • AIDO.Protein-RAG – protein modeling with MSA and structure input • AIDO.Tissue – spatially aware cell modeling
New benchmark datasets:
• Cell age prediction • Cell-type classification • Cellular perturbation (Tahoe-100M)
Utilities for distributed training and hyperparameter tuning
Use cases Includes tutorials for:
• mRNA vaccine design • Predicting protein complexes • Simulated gene knockouts for target discovery